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Insoluble material was removed by centrifugation at 30,000g for 20 min and the solubilized complex was immobilized by batch binding to M1 anti-Flag affinity resin in the presence of 5mM CaCl 2

Injectable administration further magnifies this risk by introducing the possibility of local tissue reaction, systemic inflammatory exposure, and contamination-related complications

doi: 10.1007/s43032-022-01038-2 51 SahebkarAKatsikiNWardNReinerZ