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The metabolic benefits of fat mass reduction, including improved insulin sensitivity and cardiovascular risk profile, generally outweigh concerns about proportional lean mass loss in patients with obesity

Efficacy and safety of oral semaglutide by baseline age in the PIONEER clinical trial program

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Before prescribing, I also make sure you have no contraindications to the particular medication prescribed, such as a history of pancreatitis, a personal or family history of a rare form of thyroid cancer called medullary thyroid cancer, or multiple endocrine neoplasia type 2