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There is a lot left to understand but were hopeful we can translate these discoveries to new therapies. Several sources funded the research, including the Wilmot Cancer Institute, the American Association for Cancer Research and Breast Cancer Research Foundation, Breast Cancer Coalition of Rochester, American Cancer Society, and the National Institutes of Health

1998 Mar 17;95(6):3071-6

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Although serine can be derived from the degradation of cellular proteins and the interconversion with glycine, these pathways alone are insufficient to meet the metabolic demands of biological tissues, especially in pathological conditions ( de novo serine synthesis pathway (SSP) substantially enhances the intracellular availability of serine ( The de novo serine synthesis pathway, also referred to as the serine biosynthetic pathway, is a branch pathway of glycolysis