Statistical analysis Significance testing was conducted using GraphPad Prism 6 (GraphPad software, La Jolla, CA, USA)
[18] [19] Side effects [edit] The most common side effects include gastrointestinal disorders, such as dyspepsia, decreased appetite, nausea, vomiting, abdominal pain, diarrhea
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For example, supplementing with MSM significantly reduced inflammation in mice with stomach ulcers by inhibiting the release of inflammatory cytokines including TNF- and IL-6, as well as increasing glutathione levels ( Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo ( Summary MSM may reduce the release of molecules associated with inflammation, such as TNF- and IL-6, as well as boost levels of the powerful antioxidant glutathione