Author contribution All authors contributed to the studys conception and design
Vitamin B12 deficiency becomes more common with age, affecting approximately one in 10 individuals aged 75 years or older [2,3]
Laymans terms: Think of collagen like the scaffolding for healing
Already in 1971 [i.e., 13 years after the first crystal structure of a protein, myoglobin, was solved in 1958 (Kendrew et al., 1958), and when only seven protein crystal structures were known (Minor et al., 2016)], a study on the X-ray crystal structure of staphylococcus nuclease first used the term disordered to describe two regions of missing electron density ( More recent analyses confirmed the prevalence of regions with missing electron density in protein structures deposited in the PDB (Le Gall et al., 2007
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