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The changes of C-reactive protein and adiponectin in different stages of glycometabolism and different numbers of components of metabolic syndrome

Traditional anti-inflammatory drugs, such as corticosteroids and nonsteroidal anti-inflammatory drugs, can cause side effects that affect multiple organs, including gastrointestinal and cardiovascular complications and renal failure [11]

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Here, I review this remarkable development from the earliest observations of glucose lowering and modest weight losses with native glucagon-like peptide (GLP)-1 and short acting compounds, to the recent development of highly active formulations and new molecules

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