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Providers should also review liver function, renal clearance, and any history of medullary thyroid carcinoma or thyroid nodules, as GLP-1 safety data in these populations is limited

Using smaller plates and eating meals at consistent times roughly three to five hours apart prevents the intense hunger that triggers overeating

These exist because not everyone tolerates the standard escalation jumps well

These include: Patients currently taking another GLP-1 medication cannot take semaglutide at the same time, though they may be able to switch under provider supervision

Medications If nausea remains severe despite all dietary and behavioral strategies, discuss anti-nausea medications with your provider