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In humans, acute administration of pharmacological doses of GLP-1 significantly induce satiety and reduce food intake (9193)

OTC Option: Use an osmotic laxative (Miralax) daily to keep water in the colon

Because they occur naturally in the body, they are highly specific in their functions, acting as signaling molecules that instruct cells on how to behave

And another study found that eating plain yogurt significantly increased the guts production of GLP-1