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Transient breathing discomfort or mild bronchospasm reported in some individuals, particularly those with asthma or sensitive airways

This includes confirmed low serum vitamin B12 levels, pernicious anaemia, malabsorption states such as coeliac disease, inflammatory bowel disease, or post-gastric or bariatric surgery, unexplained anaemia, neuropathy or neurological symptoms consistent with vitamin B12 deficiency, a long-term vegan diet with symptoms or low levels, or failure of oral vitamin B12 supplementation

Byrne JA, Grieve DJ, Cave AC, Shah AM: Oxidative stress and heart failure

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Uric acid affected differently the expression of enzymes involved in the metabolism of glutathione (Fig