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2 REIMAGINE 3 was a 40-week phase 3 trial evaluating the safety and efficacy of CagriSema 2.4 mg/2.4 mg and 1 mg/1 mg once weekly versus dose-matched placebo in 274 adults with T2D as add-on to once-daily basal insulin with or without metformin

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However, researchers involved in the field said some inflammation-related biomarkers showed modest changes that continue to attract scientific attention

Eli Lillys once-weekly injectable retatrutide dubbed triple G because it mimics three hormones is expected to seek FDA approval this year, with early data suggesting it could deliver an even bigger weight-loss punch than earlier GLP-1s