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To date, studies in animals and humans suggest that GLP-1 may improve hepatic lipid accumulation through signal transduction of the AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) pathway [33]

Sci Rep 12:13825

Eye (Lond) 2(Pt 4):358366 Mollan SP et al (2021) Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension: A Randomized Clinical Trial

Firstly, expanding indications is a current hotspot in GLP-1 drug research

Clinically, it is primarily used for the treatment of type 2 diabetes mellitus to lower fasting and postprandial glucose levels and HbA1c, with additional applications in chronic weight management for obese or overweight patients