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Dehydration, often precipitated by diuretics or large-volume paracentesis, reduces effective renal perfusion and may impair renal ammonia excretion, leading to increased systemic ammonia levels

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Lipid dysregulation promotes the pathogenesis of PD by oxidative stress and inflammation, such as proinflammatory lipid mediators of platelet-activating factors, which play a key role in the progressive neurodegeneration associated with -synuclein intracellular traffic in PD

Korean J Intern Med (2018) 33:1256

Forskolin effectively lowers IOP by decreasing AH production, a key therapeutic target in glaucoma (222)