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Suppositories deliver many types of medication, and a person may need to use them if they: are having seizures and cannot take medications by mouth are unable to swallow medication for any reason are vomiting and cannot keep pills or liquids down have a blockage that stops the medication moving through the digestive system People may also take suppositories if the medication: tastes too bad to take by mouth would break down too quickly in the gut could be destroyed in the gastrointestinal tract There are three types of suppositories: Rectal suppositories Rectal suppositories go in the rectum or anus

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suggests that the use of PAD4 inhibitors can reduce NETs formation and subsequently decrease organ damage (101)