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Nausea and diarrhoea are very common, and vomiting is common with GLP-1 receptor agonists according to the SmPC, and can lead to significant fluid loss

Sensitivity analyses We conducted prespecified sensitivity analyses to evaluate the robustness of the target trial emulation and to probe key threats to validity, including residual confounding, reverse causation (protopathic bias), and time-related biases

For chronic prevention of gout, the essential message is that present treatments work in a huge majority of patients and are generally well-tolerated

Assess age, weight, and frailty measures

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