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As semaglutide and tirzepatide seek to expand their approved indications, e.g., potentially adding heart failure, chronic kidney disease or MASH, following several successful phase 3 trial readouts in 2023 and 2024, more pathways open up to Medicare reimbursement of AOMs within existing rules

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Improved insulin sensitivity can influence sex hormone-binding globulin (SHBG) levels, which determines how much free testosterone and estrogen circulate in the blood

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