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The applicability of the proposed sensing strategy toward cystine was established, and the recovery percentage was between 99.8 0.4 and 101.0 2.1 for n = 3

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Combining two individually beneficial interventions does not always produce additive or synergistic results

So you always have to worry about that when you're doing an observational study

pylori infection rates have declined have also seen a decline in the incidence of gastric cancer ( via the oral-oral or fecal-oral routes, affecting over half of the population ( Helicobacter pylori infection typically occurs in childhood, with more than 30% of children being infected (Yuan et al., 2022)