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We speculate that this reliance on CI-dependent NAD regeneration, together with the dynamic demands of lipid synthesis and storage, makes CI susceptible to circadian regulation in adipose tissue
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In addition to these polar interactions, in the middle region of the cavity II, Phe4 of ghrelin packs against GHSR residues L103 2.64 , L306 7.36 , and F309 7.39 to form hydrophobic interactions (Fig
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