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The effects of increasing weekly doses of ascorbate on certain cellular and humoral immune functions in normal volunteers

Users describe it as a "slow turn" rather than sudden improvement

Immediate effects: Some patients report feeling an improvement in energy levels within 24 to 48 hours, though this varies

Previous experiments strongly suggested its involvement in experimental gastric ulcer healing

This reversal was seen also on the background of the disturbed prostaglandins- and NO-systems, prostaglandins synthesis inhibition as well as NO-overstimulation (NOS-substrate L-arginine) or NO-blockade (N(G)-nitro-L-arginine methyl ester (L-NAME)) (Stupnisek et al., 2012