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Kidney Problems: There have been reports of kidney failure and other kidney issues, particularly in patients with pre-existing kidney conditions

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Further, the authors found that reduced GLP-1+ cells in mice and inhibition of respiration in organoid cultures support a causative role for metabolism in steering differentiation

Finally, to deal with participants with no BMI information at baseline, we also carried out analyses excluding individuals with no BMI information, in addition to an analysis using multivariate imputation using chained equations for BMI missing values (see ESM Table 3 for code employed for analysis)

The diagnosis of acute pancreatitis requires the presence of two of the following three criteria: acute onset of persistent, severe, epigastric pain often radiating to the back, elevation in serum lipase or amylase to three times or greater than the upper limit of normal, and characteristic findings of acute pancreatitis on imaging (280)