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Some studies, according to the Stanford School of Medicine, have shown results around addiction treatment, from opioids to alcohol, nicotine and more

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Emotional Blunting and Mental Fatigue Some people describe feeling: Flat Unmotivated Disconnected Mentally drained This can be a sign that the medication is over-regulating dopamine , leading to emotional and cognitive fatigue rather than clarity

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doi:10.1093/ajcn/nqx082 Reynolds AN, Cummings J, Tannock G, Mann J