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Plans may differentiate by indication: a policy might cover semaglutide for T2D with minimal restrictions, but treat a Wegovy prescription with the same molecule as off-label (for weight) and therefore require stricter criteria

Food and Drug Administration (FDA) for medical, therapeutic, diagnostic, or consumptive use

They should look "milky" or cloudy, not clear

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Exceeding recommended doses (typically above 1,000 mg/day) increases the likelihood of digestive side effects such as bloating, cramping, and loose stools