Niazi and Chatham list several common symptoms that occur when starting GLP-1s or with dose adjustments: Nausea or vomiting Diarrhea or constipation Heartburn or bloating Fatigue Dehydration Muscle loss Some patients may also experience hair thinning with higher doses for prolonged periods, especially when paired with low-calorie intake
[4] However, such studies cannot prove causation, and confounding factors (such as overall health status, healthcare engagement, or socioeconomic variables) may influence these findings
Link Abdou, A
13 C NMR (100 MHz, Chloroform-d) = 163.0, 162.5, 149.3, 146.8, 138.4, 125.7, 124.7, 115.0, 114.8, 65.6, 59.4, 32.0
This risk appears linked to rapid glycemic improvement, consistent with established mechanisms observed with intensive insulin therapy