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Key Benefits : Weight loss of approximately 11% at 72 weeks on the highest dose in clinical trials

Long-term follow-up data spanning 52 weeks demonstrates sustained improvements in liver enzyme profiles and ultrasound findings of fatty infiltration

[DOI] [PubMed] [Google Scholar] 53.Rivoira MA, Marchionatti AM, Centeno VA, Daz de Barboza GE, Peralta Lpez ME, Tolosa de Talamoni NG

Obokata, M

The inverse relationship between coffee consumption and HCC is thought to be due to caffeine's alteration of liver signaling and inflammatory pathways, which lowers circulating levels of inflammatory biomarkers such as interferongamma (IFN), CX3CL1fractalkine, CCL4, FGF2, and sTNFRII (de Melo Pereira et al., 2020