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For type 2 diabetes, the modern bar isnt just does it lower the number, its does it prevent heart attacks, strokes, and kidney decline. The injectable GLP-1s earned their place by proving that in dedicated outcomes trials, and this drug will have to as well. Further research, Carroll said, should also smartly test different starting doses and escalation speeds and how they impact potential side effects, and a rigorous head-to-head comparison against what oral GLP-1 options are already available

A comparison showed that the treatment with NP4 resulted in the highest amount of lipid peroxides (Supplementary Fig

Long-term efficacy and safety of oral semaglutide and the effect of switching from sitagliptin to oral semaglutide in patients with type 2 diabetes: A 52-week, randomized, open-label extension of the PIONEER 7 trial

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