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the AITC treatment increased even more the difference for pad2-1 through the concentration range than for the WT, whereas the reduction between the two highest doses of BSO was less pronounced on the mutant compared to WT
213 Instead, inhibition of the H 2 S-synthesising trans-sulphuration pathway enzymes CBS and CSE, together with 3-MST, still holds great promise for cancer treatment, 81,143,214 as outlined below
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