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At the adaptive interface, NETs support T helper 17 (Th17) differentiation through TLR2-STAT3 signaling, enhancing IL-6 and IL-17 release, thereby amplifying neutrophil-driven inflammation [82]

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The management of ulcerative colitis in the UK is guided by NICE Clinical Guideline NG130 (Ulcerative colitis: management), which provides comprehensive, evidence-based recommendations for both adults and children