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To further ascertain the translatability of the novel effects of CT as a treatment for biofilm infections will require in vivo study in a mammalian model of lung infection and other in vivo sites, and an analysis of factors linked to the hosts intrinsic immune response against bacterial infections

Al-Zaidy SA, Sahenk Z, Rodino-Klapac LR, Kaspar B, Mendell JR

Dahlin, L

Because of this, less GUDCA is produced, FXR remains activated, fewer L-cells are formed, and GLP-1 production falls

Targeting microbial pathways with drugs or phages A nascent but exciting area is using targeted therapies to modulate the microbiome without necessarily adding anything new