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5.2.4 Novel pharmacotherapies and combination treatment As a multifactorial degenerative disease, OA often responds poorly to single-target therapies ( Increasingly, ferroptosis is recognized as central to the multifaceted and dynamic pathophysiology of OA

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This is significantly higher than the standard recommendations of 13 cups for men and 9 cups for women , reflecting the increased hydration needs of patients on these medications.However, it's not just about quantity the quality and timing of hydration matter enormously

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