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found that circ_0000808 was upregulated in NSCLC cells, where it enhanced the expression of the Gln transporter SLC1A5 by interacting with miR1827, thereby promoting Gln metabolism and facilitating the progression of NSCLC (56)

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Both mechanisms increase cytoplasmic concentrations of dopamine (DA), norepinephrine (NE), and serotonin (5-HT), producing a cytoplasmic surge of monoamines