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In addition, high level of LDL-C can cause ectopic lipid deposition and associated metabolic diseases, such as non-alcoholic fatty liver disease ( Gut microbiota regulates several diseases, including liver diseases ( Microbial effects on cholesterol metabolism Gut microbiota, which is influenced by diet and living environment, is individually unique and highly related to cholesterol metabolism ( The SCFAs, BAs, TMAO, and LPS are major gut microbiota metabolites that broadly affect the human cholesterol metabolism
For example, Khan et al
Jilin Science and Technology Agency funds in China, 20200301005RQ
Ketogenic diet with medium-chain triglycerides restores skeletal muscle function and pathology in a rat model of duchenne muscular dystrophy
The 2022 ASMBS/IFSO guidelines also support consideration in patients with BMI 30 kg/m with metabolic disease
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