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The applicant noted, however, that the Medicare Claims Processing Manual's definition for C1763 clarifies that these matrices are intended to repair or support damaged or inadequate soft tissue and are typically used for urinary incontinence ( e.g., pelvic floor repair) or to reinforce soft tissues where weakness exists in the urological or musculoskeletal anatomy, explicitly excluding products used as skin replacements

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397 CRISPR-Cas9-engineered human iPSCs with truncated HNF1 p291FsinSCs grown as 3D pancreatic organoids were shown to abolish HNF1 function and reduce pancreatic progenitor and -cell differentiation