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It has been demonstrated that the formation of intra-tumor hypoxia following the injection of antiangiogenic drugs increases the subpopulation of cells with stem characteristics in glioblastoma, breast cancer, and lung cancer [68,69,70]

Morton JT, Jin DM, Mills RH, Shao Y, Rahman G, McDonald D, Zhu Q, Balaban M, Jiang Y, Cantrell K, Gonzalez A, Carmel J, Frankiensztajn LM, Martin-Brevet S, Berding K, Needham BD, Zurita MF, David M, Averina OV, Taroncher-Oldenburg G

The traditional way to open the joint is to place a large padded post in the patients perineal area to provide counter-traction while the leg is pulled taught

(1996) 271:E108391

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