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Their effects on weight regulation, insulin sensitivity, and liver health could offer long-term benefits, particularly in condiBeltagi, MD, PhD, Chief Physician, Professortions such as obesity, type 2 diabetes, and metabolic dysfunction associated steatotic liver disease

On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

These findings suggest that GLP-1R-independent renoprotective effects are mediated by GLP-1 cleavage products

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High seminal OS in infertile men with varicocele has been associated with low conventional sperm parameters [12, 13] and increased sperm DNA fragmentation (SDF) [12, 14]