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doi: 10.1152/ajpendo.00577.2005 49 NakamuraTTanimotoHMizunoYOkamotoMTakeuchiMTsubamotoYet al

(Lond.) 37 , 14431451 (2013)

Synthetic drugs, typically administered via injection, offer potent and rapid effects, making them highly effective for managing severe type 2 diabetes and obesity

In clinical research, that effect is often reflected through body weight reduction and waist circumference change over defined protocol windows, and those endpoints are exactly what the phase 2 cagrilintide trial reported

Purtell advises focusing on achieving sustainable weight loss rather than fixating on a specific number on the scale