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To mitigate IGF-1 side effects such as joint pain, swelling, and nerve compression, bodybuilders can follow several strategies: use the lowest effective dose under medical supervision, rotate injection sites, maintain proper hydration, support joints with supplements like glucosamine or omega-3 fatty acids, and incorporate stretching and mobility exercises
Dosing Information Recommended Dose : The typical maximum dose for ipamorelin is 100 micrograms
Research suggests that activation of these receptors may increase hunger cues and could contribute to changes in body composition, including potential increases in adiposity
Genes Dev 2003