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Most of the chemotherapeutic agents act by producing free radicals that cause cellular damage and necrosis of malignant cells as part of their mode of action in cancer treatment

Additionally, RANKL emerged as a potential link between DPP-4 and bone-energy metabolism, as it induced DPP-4 expression in osteoclasts, leading to decreased GLP-1 levels and increased blood glucose (Fig

While reduced appetite is completely normal on GLP-1s, skipping meals entirely is not recommended

Prophylactic treatment with transdermal deferoxamine mitigates radiation-induced skin fibrosis

Sun exposure and vitamin D are also beneficial