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As with other G protein-coupled receptors, GPER-1 is a seven-transmembrane domains receptor located at the plasma membrane, with its amino and carboxyl groups oriented to the extra- and intracellular environments, respectively (Figures 2, 3

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Ma PC, Tretiakova MS, MacKinnon AC, Ramnath N, Johnson C, Dietrich S, et al

Inducing ferroptosis: Sensitization strategy for radiotherapy and its application

Shadyro O, Samovich S, Edimecheva I