Tetramethylpyrazine (TMP), an active component in both CHF and the medicinal herbs Ligusticum wallichii (Chuanxiong) , has the potential to prevent AKI via a variety of processes, including ameliorating oxidative stress damage, suppressing inflammatory responses, deterring apoptotic cell death of intrinsic renal cells, and modulating autophagy (Gong, 2018
each one depletes glutathione through a direct biochemical mechanism
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Consult your healthcare professional before use if pregnant, nursing, taking medications, or for any use by minors
