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In experiments with mice, the introduction of FOX04-DRI successfully caused senescent cells to die

Zhang Q, Li Y, Yin C, Yu J, Zhao J, Yan L, Wang Q

Immunofluorescent findings reveal that RSL3 alters the availability of two crucial proteins, which play important roles in DNA stability and repair

Stromal cells Cancer-associated fibroblasts (CAFs) are essential components of the TME with multiple roles, encompassing stromal remodeling and deposition, extensive bidirectional signaling interactions with cancer cells, and communication with immune cells

Its primary role is to stimulate collagen and elastin production in the dermis, promote antioxidant defenses, and activate genes associated with tissue remodeling and wound repair