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Premature removal of the needle or rapid injection can increase local tissue damage and subsequent itching

GLP-1 receptor agonists are synthetic analogs or modified versions of this endogenous hormone, designed to resist degradation by the enzyme dipeptidyl peptidase-4 (DPP-4), thereby extending their duration of action from minutes to hours or days

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The proliferation of NPCs is enhanced by anti-depressive treatments, seizures, and physical activity, whereas their fate determination and maturation are strongly impaired in aging and stress (Zhao et al., 2008)