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However, note that fructose may promote tumor growth by inducing transketolase flux for nucleic-acid synthesis, as it has been shown in pancreatic cancers 199 , or stimulating angiogenesis 200

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However, individuals with copper metabolism disorders require caution

Structural features and signaling mechanisms of GPER Structural characteristics of GPER GPER, initially called G protein-coupled receptor 30 (GPR30) in the 1990 s [9, 10], mediates the nongenomic effects of 17-estradiol via mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase 1/2 (ERK-1/2)