Prespecified subgroup, sensitivity and specificity analyses Subgroup analyses were conducted based on gender, age, body mass index (BMI), HbA1c, DM status (pre-existing or post-transplant), post-transplant eGFR, the presence of hypertension, proteinuria, heart failure, obesity, enrollment time, prior history of GLP-1RAs uses before transplant, and the concurrent use of medications, including ACEIs/ARBs, antidiabetic agents (insulin, metformin, dipeptidyl peptidase-4 inhibitors (DPP-4is), sodium-glucose cotransporter 2 inhibitors (SGLT2is), and immunosuppressants (steroids, cyclosporine and tacrolimus)
Malabsorption due to digestive disorders, such as Crohns disease or celiac disease, can also lead to vitamin B12 deficiency
These medications are serious treatments that licensed doctors must approve, sticking to proven medical standards
[57] Nguyen MM, Ahmann FR, Nagle RB, et al
doi: 10.1080/07391102.2021.1886172