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Human clinical trials establishing these effects have not been completed and conclusions about efficacy in humans should not be drawn from this data alone

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*Correspondence: Liping Qu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination