is semaglutide used for pcos and metformin improve menstrual cyclicity in overweight/obese women with polycystic ovary syndrome: a randomized trial The Truth About Ozempic for

A drug that is right for someone with type 2 diabetes and heart disease risk may not have the same benefit-to-risk profile for a metabolically healthy person trying to optimize performance and that distinction matters

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No head-to-head trials exist.

Safety not established in pregnancy or breastfeeding

The role of GIP in energy balance is further complicated by paradoxical findings that mice overexpressing Gip were leaner than wild type controls, when fed either a standard-chow or HFD (70)