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Tirzepatide has an FDA boxed warningthe highest level of safety alertdue to an increased risk of thyroid C-cell tumors observed in animal studies

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When our friend tirzepatide received its FDA approval for weight loss, and simultaneously telehealth platforms increased prescribing of GLP-1s for patients, we saw this shortage situation explode

In our model, the absence of TrkB signalling in iSPN + led to specific upregulation of Gsto2 at the pre-symptomatic stage, followed by a sharp decrease to baseline levels by 8 months (Fig

Thiol-ene chemistry has been applied less extensively in other areas of peptide science such as tagging of peptides or in probes