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"Glucose-dependent insulinotropic polypeptide receptor-expressing cells in the hypothalamus regulate food intake." Cell Metabolism , 30(5), 987-996

They are not off-label drugs

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Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a syndrome of inherited cancers, including cutaneous leiomyomas (CLMs), uterine fibroids, and aggressive kidney tumors (Tomlinson et al., 2002)

Role of insulin in neurotrauma and neurodegeneration: a review