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This chronic, systemic depletion allows environmental toxins and latent, dormant infections (such as EBV or human herpesviruses) to reactivate and accumulate, continuously driving immune dysfunction, mast cell activation syndrome (MCAS), and unrelenting fatigue

Alcohol makes this problem worse in two ways: it directly worsens the toxic effects of GHB, and it impairs the judgment needed to dose carefully or recognize early warning signs

Energy demand increases, particularly during physical exertion

Further, staying hydrated enhances the advantages of glutathione for the pores and skin and aids in detoxification