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The FDA found that Verve was "appropriate for the protection of the public health" based in part on a review of data showing that "youth, nonsmokers, and former smokers are unlikely to initiate or reinitiate tobacco use with these products." Product performance will be monitored over the next few years for emerging ill effects
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Regarding sufficiency (Are additional studies needed to establish the existence of the phenomenon?), from the beginning of this cumulative meta-analysis, the 95% CIs around the OR included the final average effect size (ES) obtained at the end of the cumulative meta-analysis
