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however, there are brands in Germany having measured nicotine content surpassing 50 mg with freebase nicotine over 90%.9 42 43 The information regarding the toxicity and addictiveness of these products is limited and further research into the safety of these high nicotine content pouches is necessary

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References Abdelghany TM et al (2018) Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase

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Because they are not combustible, electronic, or classified as liquids, they are generally permitted in both hand luggage and checked baggage