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North America leads with 34.6% revenue share in 2025, driven by FDA PMTA-authorized product expansion, mature DTC online retail infrastructure, and strong consumer trust in compliant e-cigarette brands across the United States and Canada

PLoS ONE 11 , e0156348 (2016)

The increased risk of developing dementia, particularly Alzheimers disease and vascular dementia, is linked with current smoking, and smoking cessation is a risk reducer

In fact, it's hard work being a smoker, as we added the onset of early withdrawal to most stressful events